第四军医大学西京医院肝胆外科的论文被撤稿:论文存在重复,细胞系存在问题
研发家 | 2024-05-11 0

01

论文信息

 

2013年2月28日,第四军医大学西京医院肝胆外科在PLoS ONE(中科院三区,IF=3.7)期刊上在线发表论文,标题为“The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma”(Notch1 与 Notch3 相比在肝细胞癌高转移和总生存期差中的意义)。

 

通讯作者:第四军医大学西京医院 Kefeng Dou(音译 窦科峰)

第一作者:第四军医大学西京医院Liang Zhou ,Ning Zhang ,Wenjie Song ,Nan You

02

质疑信息

 

质疑一:八篇论文共享图像。

 

Figure 2: There are three overlapping parts, described as showing different experimental conditions.

This is part of a series of eight papers sharing images between them, it is worth noting that there are rotations, incomplete overlaps, differences in zoom, and in some cases significant differences between photos that share some regions of similarity, perhaps they were edited, or the images show the same cells imaged at different times. I'll include a large diagram below, which is admittedly rather difficult to track with the multiple colours, but I hope the authors can pick out their paper and figure out what's happened here.

 

Relevant papers:

  • 10.1371/journal.pone.0124338

  • 10.12659/MSM.909450

  • 10.3892/mmr.2019.10636

  • 10.3390/ijms160921643

  • 10.1371/journal.pone.0097406

  • 10.1007/s13277-015-3396-0

  • 10.1371/journal.pone.0057382

  • 10.1038/s41417-018-0031-4

03

撤稿原因

 

已于2024年4月2日被撤回。

本文的担忧影响了图2和图3中显示的结果,以及本研究中使用的细胞系。第一作者LZ表示,在图2A MHCC97H结果的制备过程中出现了错误,并提供了替代数据。然而,在对这些数据进行编辑审查时,观察到额外的部分面板重叠。

鉴于对报告数据的有效性和可靠性提出质疑的未解决问题,PLOS ONE 编辑撤回了本文。

参考信息:

https://pubmed.ncbi.nlm.nih.gov/23468978/

https://pubpeer.com/publications/34F90956E24551FE93F90E3A94C760#3

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